| Ident. | Authors (with country if any) | Title |
|---|
| 000595 |
Sawan Kumar Jha [Finlande] ; Khushbu Rauniyar [Finlande] ; Terhi Karpanen [Norvège] ; Veli-Matti Lepp Nen [Finlande] ; Pascal Brouillard [Belgique] ; Miikka Vikkula [Belgique] ; Kari Alitalo [Finlande] ; Michael Jeltsch [Finlande] | Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1 |
| 000E67 |
Aleksanteri Aspelund [Finlande] ; Marius R. Robciuc [Finlande] ; Sinem Karaman [Finlande] ; Taija Makinen [Finlande] ; Kari Alitalo [Finlande] | Lymphatic System in Cardiovascular Medicine. |
| 001568 |
Lukas Stanczuk [Royaume-Uni] ; Ines Martinez-Corral [Royaume-Uni] ; Maria H. Ulvmar [Suède] ; Yang Zhang [Suède] ; Bàrbara Lavi A [Suède] ; Marcus Fruttiger [Royaume-Uni] ; Ralf H. Adams [Allemagne] ; Dieter Saur [Allemagne] ; Christer Betsholtz [Suède] ; Sagrario Ortega [Espagne] ; Kari Alitalo [Finlande] ; Mariona Graupera [Espagne] ; Taija M Kinen [Royaume-Uni] | cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels. |
| 001634 |
Harri Nurmi ; Pipsa Saharinen ; Georgia Zarkada ; Wei Zheng ; Marius R. Robciuc ; Kari Alitalo [Finlande] | VEGF-C is required for intestinal lymphatic vessel maintenance and lipid absorption |
| 001D28 |
Tomi V. Tervala [Finlande] ; Pauliina Hartiala [Finlande] ; Tuomas Tammela [Finlande] ; Mikko T. Visuri [Finlande] ; Seppo Yl Herttuala [Finlande] ; Kari Alitalo [Finlande] ; Anne M. Saarikko [Finlande] | Growth factor therapy and lymph node graft for lymphedema. |
| 001D60 |
M Guy Roukens ; Josi Peterson-Maduro ; Yvonne Padberg ; Michael Jeltsch ; Veli-Matti Lepp Nen ; Frank L. Bos ; Kari Alitalo [Finlande] ; Stefan Schulte-Merker ; Dörte Schulte [Allemagne] | Functional Dissection of the CCBE1 Protein: A Crucial Requirement for the Collagen Repeat Domain. |
| 002222 |
Aleksanteri Aspelund ; Salli Antila ; Steven T. Proulx ; Tine Veronica Karlsen ; Sinem Karaman ; Michael Detmar ; Helge Wiig ; Kari Alitalo [Finlande] | A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules |
| 002445 |
R. Sathish Srinivasan ; Noelia Escobedo ; Ying Yang ; Ashley Interiano ; Miriam E. Dillard ; David Finkelstein [États-Unis] ; Suraj Mukatira [États-Unis] ; Hyea Jin Gil ; Harri Nurmi [Finlande] ; Kari Alitalo [Finlande] ; Guillermo Oliver | The Prox1–Vegfr3 feedback loop maintains the identity and the number of lymphatic endothelial cell progenitors |
| 002894 |
Dae-Young Park [Corée du Sud] ; Junyeop Lee [Corée du Sud] ; Intae Park [Corée du Sud] ; Dongwon Choi [États-Unis] ; Sunju Lee [États-Unis] ; Sukhyun Song [Corée du Sud] ; Yoonha Hwang [Corée du Sud] ; Ki Yong Hong [Corée du Sud] ; Yoshikazu Nakaoka [Japon] ; Taija Makinen [Suède] ; Pilhan Kim [Corée du Sud] ; Kari Alitalo [Finlande] ; Young-Kwon Hong [États-Unis] ; Gou Young Koh [Corée du Sud] | Lymphatic regulator PROX1 determines Schlemm’s canal integrity and
identity |
| 002910 |
Wei Zheng ; Aleksanteri Aspelund ; Kari Alitalo [Finlande] | Lymphangiogenic factors, mechanisms, and applications |
| 002954 |
Taina Vuorio [Finlande] ; Harri Nurmi [Finlande] ; Karen Moulton [États-Unis] ; Jere Pikkarainen [Finlande] ; Marius R. Robciuc [Finlande] ; Miina Öhman [Finlande] ; Suvi E. Heinonen [Finlande] ; Haritha Samaranayake [Finlande] ; Tommi Heikura [Finlande] ; Kari Alitalo [Finlande] ; Seppo Yl Herttuala [Finlande] | LYMPHATIC VESSEL INSUFFICIENCY IN HYPERCHOLESTEROLEMIC MICE ALTERS LIPOPROTEIN LEVELS AND PROMOTES ATHEROGENESIS |
| 002C90 |
Michael Jeltsch [Finlande] ; Sawan Kumar Jha ; Denis Tvorogov ; Andrey Anisimov ; Veli-Matti Lepp Nen ; Tanja Holopainen ; Riikka Kivel ; Sagrario Ortega ; Terhi K Rpanen ; Kari Alitalo [Finlande] | CCBE1 enhances lymphangiogenesis via A disintegrin and metalloprotease with thrombospondin motifs-3-mediated vascular endothelial growth factor-C activation. |
| 002D09 |
Sinem Karaman [Suisse] ; Maija Hollmén [Suisse] ; Marius R. Robciuc [Finlande] ; Annamari Alitalo [Suisse] ; Harri Nurmi [Finlande] ; Bettina Morf [Suisse] ; Dorina Buschle [Suisse] ; H. Furkan Alkan [Suisse] ; Alexandra M. Ochsenbein [Suisse] ; Kari Alitalo [Finlande] ; Christian Wolfrum [Suisse] ; Michael Detmar [Suisse] | Blockade of VEGF-C and VEGF-D modulates adipose tissue inflammation and improves metabolic parameters under high-fat diet |
| 002D54 |
Wei Zheng [Finlande] ; Harri Nurmi [Finlande] ; Sila Appak [Allemagne] ; Amélie Sabine [Suisse] ; Esther Bovay [Suisse] ; Emilia A. Korhonen [Finlande] ; Fabrizio Orsenigo [Italie] ; Marja Lohela [Finlande] ; Gabriela D Mico [Finlande] ; Tanja Holopainen [Finlande] ; Ching Ching Leow [États-Unis] ; Elisabetta Dejana [Italie] ; Tatiana V. Petrova [Suisse] ; Hellmut G. Augustin [Allemagne] ; Kari Alitalo [Finlande] | Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions |
| 003063 |
Hyouk-Bum Kwon [Japon] ; Shigetomo Fukuhara [Japon] ; Kazuhide Asakawa [Japon] ; Koji Ando [Japon] ; Takeru Kashiwada [Japon] ; Koichi Kawakami [Japon] ; Masahiko Hibi [Japon] ; Young-Guen Kwon [Corée du Sud] ; Kyu-Won Kim [Corée du Sud] ; Kari Alitalo [Finlande] ; Naoki Mochizuki [Japon] | The parallel growth of motoneuron axons with the dorsal aorta depends on Vegfc/Vegfr3 signaling in zebrafish |
| 003130 |
Veli-Matti Lepp Nen [Finlande] ; Denis Tvorogov [Finlande] ; Kaisa Kisko [Suisse] ; Andrea E. Prota [Suisse] ; Michael Jeltsch [Finlande] ; Andrey Anisimov [Finlande] ; Sandra Markovic-Mueller [Suisse] ; Edward Stuttfeld [Suisse] ; Kenneth N. Goldie [Suisse] ; Kurt Ballmer-Hofer [Suisse] ; Kari Alitalo [Finlande] | Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation |
| 003229 |
Michael Jeltsch [Finlande] ; Veli-Matti Lepp Nen [Finlande] ; Pipsa Saharinen [Finlande] ; Kari Alitalo [Finlande] | Receptor Tyrosine Kinase-Mediated Angiogenesis |
| 003542 |
Jean-Leon Thomas ; Kasey Baker ; Jinah Han ; Charles Calvo ; Harri Nurmi ; Anne C. Eichmann ; Kari Alitalo [Finlande] | Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells |
| 003561 |
C E Markhus [Norvège] ; T V Karlsen ; Marek Wagner ; M. Wagner ; S. Svendsen ; O. Tenstad ; Kari Alitalo [Finlande] ; H. Wiig | Increased interstitial protein because of impaired lymph drainage does not induce fibrosis and inflammation in lymphedema. |
| 003578 |
Helge Wiig [Norvège] ; Agnes Schröder [Allemagne] ; Wolfgang Neuhofer [Allemagne] ; Jonathan Jantsch [Allemagne] ; Christoph Kopp [Allemagne] ; Tine V. Karlsen [Norvège] ; Michael Boschmann [Allemagne] ; Jennifer Goss [Allemagne] ; Maija Bry [Finlande] ; Natalia Rakova [Allemagne] ; Anke Dahlmann [Allemagne] ; Sven Brenner [Allemagne] ; Olav Tenstad [Norvège] ; Harri Nurmi [Finlande] ; Eero Mervaala [Finlande] ; Hubertus Wagner [Allemagne] ; Franz-Xaver Beck [Allemagne] ; Dominik N. Müller [Allemagne] ; Dontscho Kerjaschki [Autriche] ; Friedrich C. Luft [Allemagne, États-Unis] ; David G. Harrison [États-Unis] ; Kari Alitalo [Finlande] ; Jens Titze [Allemagne, États-Unis] | Immune cells control skin lymphatic electrolyte homeostasis and blood pressure |
| 003927 |
Jacques A. Villefranc [États-Unis] ; Stefania Nicoli [États-Unis] ; Katie Bentley [Royaume-Uni] ; Michael Jeltsch [Finlande] ; Georgia Zarkada [Finlande] ; John C. Moore [États-Unis] ; Holger Gerhardt [Royaume-Uni] ; Kari Alitalo [Finlande] ; Nathan D. Lawson [États-Unis] | A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development |
| 003C44 |
René H Gerling [Allemagne] ; Cathrin Pollmann [Allemagne] ; Martin Andreas [Allemagne] ; Christian Schmidt [Allemagne] ; Harri Nurmi [Finlande] ; Ralf H. Adams [Allemagne] ; Kari Alitalo [Finlande] ; Volker Andresen [Allemagne] ; Stefan Schulte-Merker [Pays-Bas] ; Friedemann Kiefer [Allemagne] | A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy |
| 004234 |
Susan N. Thomas ; Joseph M. Rutkowski ; Miriella Pasquier ; Emma L. Kuan [États-Unis] ; Kari Alitalo [Finlande] ; Gwendalyn J. Randolph [États-Unis] ; Melody A. Swartz | Impaired humoral immunity and tolerance in K14-VEGFR-3-Ig mice that lack dermal lymphatic drainage |
| 004331 |
Momina Mirza [Suède] ; Mei-Fong Pang [Suède] ; Mohamad Amr Zaini [Suède] ; Paula Haiko [Finlande] ; Tuomas Tammela [Finlande] ; Kari Alitalo [Finlande] ; Lennart Philipson [Suède] ; Jonas Fuxe [Suède] ; Kerstin Sollerbrant [Suède] | Essential Role of the Coxsackie - and Adenovirus Receptor (CAR) in Development of the Lymphatic System in Mice |
| 004852 |
Minna Sopo [Finlande] ; Maarit Anttila [Finlande] ; Hanna Sallinen [Finlande] ; Laura Tuppurainen [Finlande] ; Anniina Laurema [Finlande] ; Svetlana Laidinen [Finlande] ; Kirsi Hamalainen [Finlande] ; Pasi Tuunanen [Finlande] ; Jonna K. Koponen [Finlande] ; Veli-Matti Kosma [Finlande] ; Seppo Heinonen [Finlande] ; Kari Alitalo [Finlande] ; Seppo Yla-Herttuala [Finlande] | Antiangiogenic gene therapy with soluble VEGF‐receptors ‐1, ‐2 and ‐3 together with paclitaxel prolongs survival of mice with human ovarian carcinoma |
| 004A02 |
Charles-Félix Calvo [France] ; Romain H. Fontaine [France] ; Jihane Soueid [France] ; Tuomas Tammela [Finlande] ; Taija Makinen [Finlande] ; Clara Alfaro-Cervello [Espagne] ; Fabien Bonnaud [Royaume-Uni] ; Andres Miguez [France] ; Lucile Benhaim [France] ; Yunling Xu [France] ; Maria-José Barallobre [Espagne] ; Imane Moutkine [France] ; Johannes Lyytikk [Finlande] ; Turgut Tatlisumak [Finlande] ; Bronislaw Pytowski [États-Unis] ; Bernard Zalc [France] ; William Richardson [Royaume-Uni] ; Nicoletta Kessaris [Royaume-Uni] ; Jose Manuel Garcia-Verdugo [Espagne] ; Kari Alitalo [Finlande] ; Anne Eichmann [France, États-Unis] ; Jean-Léon Thomas [France, États-Unis] | Vascular endothelial growth factor receptor 3 directly regulates murine neurogenesis |
| 004A56 |
Kari Alitalo [Finlande] | The lymphatic vasculature in disease. |
| 004B35 |
Hanseul Yang [Corée du Sud] ; Chan Kim [Corée du Sud] ; Min-Ju Kim [Corée du Sud] ; Reto A. Schwendener [Suisse] ; Kari Alitalo [Finlande] ; Warren Heston [États-Unis] ; Injune Kim [Corée du Sud] ; Wun-Jae Kim [Corée du Sud] ; Gou Young Koh [Corée du Sud] | Soluble vascular endothelial growth factor receptor-3 suppresses lymphangiogenesis and lymphatic metastasis in bladder cancer |
| 004E57 |
Markku L Hteenvuo [Finlande] ; Krista Honkonen ; Tomi Tervala ; Tuomas Tammela ; Erkki Suominen ; Johanna L Hteenvuo ; Ivana Kholová ; Kari Alitalo [Finlande] ; Seppo Yl Herttuala ; Anne Saaristo | Growth factor therapy and autologous lymph node transfer in lymphedema. |
| 005055 |
Camilla Norrmén [Finlande] ; Tuomas Tammela ; Tatiana V. Petrova ; Kari Alitalo [Finlande] | Biological basis of therapeutic lymphangiogenesis. |
| 005100 |
Reto Huggenberger ; Shoib S. Siddiqui ; Daniela Brander ; Stefan Ullmann ; Kathrin Zimmermann ; Maria Antsiferova [Suisse] ; Sabine Werner [Suisse] ; Kari Alitalo [Finlande] ; Michael Detmar | An important role of lymphatic vessel activation in limiting acute inflammation |
| 005177 |
Tuomas Tammela [Finlande] ; Georgia Zarkada [Finlande] ; Harri Nurmi [Finlande] ; Lars Jakobsson [Royaume-Uni] ; Krista Heinolainen [Finlande] ; Denis Tvorogov [Finlande] ; Wei Zheng [Finlande] ; Claudio A. Franco [Royaume-Uni] ; Aino Murtomki [Finlande] ; Evelyn Aranda [États-Unis] ; Naoyuki Miura [Japon] ; Seppo Yl-Herttuala [Finlande] ; Marcus Fruttiger [Royaume-Uni] ; Taija Mkinen [Finlande] ; Anne Eichmann [France] ; Jeffrey W. Pollard [États-Unis] ; Holger Gerhardt [Royaume-Uni, Belgique] ; Kari Alitalo [Finlande] | VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling |
| 005260 |
Tanja Holopainen ; Maija Bry [Finlande] ; Kari Alitalo [Finlande] ; Anne Saaristo [Finlande] | Perspectives on lymphangiogenesis and angiogenesis in cancer |
| 005454 |
Markku L Hteenvuo [Finlande] ; Krista Honkonen [Finlande] ; Tomi Tervala [Turquie] ; Tuomas Tammela [Finlande] ; Erkki Suominen [Turquie] ; Johanna L Hteenvuo [Finlande] ; Ivana Kholova [Finlande] ; Kari Alitalo [Finlande] ; Seppo Yl Herttuala [Finlande] ; Anne Saaristo [Turquie, Finlande] | Growth Factor Therapy and Autologous Lymph Node Transfer in Lymphedema |
| 005466 |
Camilla Norrmen [Finlande] ; Tuomas Tammela [Finlande] ; Tatiana V. Petrova [Suisse] ; Kari Alitalo [Finlande] | Biological Basis of Therapeutic Lymphangiogenesis |
| 005601 |
Reto Huggenberger ; Stefan Ullmann ; Steven T. Proulx ; Bronislaw Pytowski ; Kari Alitalo [Finlande] ; Michael Detmar | Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation |
| 005636 |
Karlien Hermans [Belgique] ; Filip Claes [Belgique] ; Wouter Vandevelde [Belgique] ; Wei Zheng [Finlande] ; Ilse Geudens [Belgique] ; Fabrizio Orsenigo [Italie] ; Frederik De Smet [Belgique] ; Evisa Gjini [Pays-Bas] ; Kristof Anthonis [Belgique] ; Bin Ren [États-Unis] ; Dontcho Kerjaschki [Autriche] ; Monica Autiero [Belgique] ; Annelii Ny [Belgique] ; Michael Simons [États-Unis] ; Mieke Dewerchin [Belgique] ; Stefan Schulte-Merker [Pays-Bas] ; Elisabetta Dejana [Italie] ; Kari Alitalo [Finlande] ; Peter Carmeliet [Belgique] | Role of synectin in lymphatic development in zebrafish and frogs |
| 005737 |
Yunling Xu ; Li Yuan ; Judy Mak ; Luc Pardanaud ; Maresa Caunt ; Ian Kasman ; Bruno Larrivée ; Raquel Del Toro ; Steven Suchting ; Alexander Medvinsky ; Jillian Silva ; Jian Yang ; Jean-Léon Thomas ; Alexander W. Koch ; Kari Alitalo [Finlande] ; Anne Eichmann ; Anil Bagri | Neuropilin-2 mediates VEGF-C–induced lymphatic sprouting together with VEGFR3 |
| 005802 |
Tuomas Tammela [Finlande] ; Kari Alitalo [Finlande] | Lymphangiogenesis: Molecular mechanisms and future promise. |
| 005812 |
Camilla Norrmén [Finlande] ; Wouter Vandevelde [Belgique] ; Annelii Ny [Belgique] ; Pipsa Saharinen [Finlande] ; Massimiliano Gentile [Finlande] ; Guttorm Haraldsen [Norvège] ; Pauli Puolakkainen [Finlande] ; Eugene Lukanidin [Danemark] ; Mieke Dewerchin [Belgique] ; Kari Alitalo [Finlande] ; Tatiana V. Petrova [Finlande] | Liprin β1 is highly expressed in lymphatic vasculature and is important for lymphatic vessel integrity |
| 005863 |
Pipsa Saharinen [Finlande] ; Maija Bry ; Kari Alitalo [Finlande] | How do angiopoietins Tie in with vascular endothelial growth factors? |
| 005922 |
Harold Kim [Canada] ; Vicky Pkh Nguyen [Canada] ; Tatiana V. Petrova [Finlande] ; Maribelle Cruz [Canada] ; Kari Alitalo [Finlande] ; Daniel J. Dumont [Canada] | Embryonic vascular endothelial cells are malleable to reprogramming via Prox1 to a lymphatic gene signature |
| 005985 |
Pipsa Saharinen [Finlande] ; Hanna Helotera [Finlande] ; Juho Miettinen [Finlande] ; Camilla Norrmen [Finlande] ; Gabriela D'Amico [Finlande] ; Michael Jeltsch [Finlande] ; Tobias Langenberg [Belgique] ; Wouter Vandevelde [Belgique] ; Annelii Ny [Belgique] ; Mieke Dewerchin [Belgique] ; Peter Carmeliet [Belgique] ; Kari Alitalo [Finlande] | Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development |
| 005A36 |
Fei Zhou [République populaire de Chine] ; Zai Chang [République populaire de Chine] ; Luqing Zhang [République populaire de Chine] ; Young-Kwon Hong [États-Unis] ; Bin Shen [République populaire de Chine] ; Bo Wang [République populaire de Chine] ; Fan Zhang [République populaire de Chine] ; Guangming Lu [République populaire de Chine] ; Denis Tvorogov [Finlande] ; Kari Alitalo [Finlande] ; Brian A. Hemmings [Suisse] ; Zhongzhou Yang [République populaire de Chine] ; Yulong He [République populaire de Chine] | Akt/Protein Kinase B Is Required for Lymphatic Network Formation, Remodeling, and Valve Development |
| 005E90 |
Joseph M. Rutkowski [Suisse] ; Carl Erik Markhus [Norvège] ; Christina C. Gyenge [Norvège] ; Kari Alitalo [Finlande] ; Helge Wiig [Norvège] ; Melody A. Swartz [Suisse] | Dermal Collagen and Lipid Deposition Correlate with Tissue Swelling and Hydraulic Conductivity in Murine Primary Lymphedema |
| 005F55 |
Marja Lohela [Finlande] ; Maija Bry ; Tuomas Tammela ; Kari Alitalo [Finlande] | VEGFs and receptors involved in angiogenesis versus lymphangiogenesis. |
| 006128 |
Carla Mouta-Bellum ; Aleksander Kirov ; Laura Miceli-Libby ; Maria L. Mancini ; Tatiana V. Petrova ; Lucy Liaw ; Igor Prudovsky ; Philip E. Thorpe [États-Unis] ; Naoyuki Miura ; Lewis C. Cantley [États-Unis] ; Kari Alitalo [Finlande] ; David A. Fruman [États-Unis] ; Calvin P. H. Vary | Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85α, p55α, and p50α |
| 006273 |
Valerie L R M. Verstraeten ; Wolfgang Holnthoner ; Maurice A M. Van Steensel ; Joep C J M. Veraart ; Reno S. Bladergroen ; Caroline A. Heckman ; Salla Keskitalo ; Jorge Frank ; Kari Alitalo [Finlande] ; Michel Van Geel ; Peter M. Steijlen | Functional analysis of FLT4 mutations associated with Nonne-Milroy lymphedema. |
| 006287 |
Camilla Norrmén ; Konstantin I. Ivanov ; Jianpin Cheng ; Nadine Zangger ; Mauro Delorenzi ; Muriel Jaquet ; Naoyuki Miura ; Pauli Puolakkainen ; Valerie Horsley ; Junhao Hu ; Hellmut G. Augustin ; Seppo Yl Herttuala ; Kari Alitalo [Finlande] ; Tatiana V. Petrova | FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1 |
| 006415 |
Andrey Anisimov [Finlande] ; Annamari Alitalo [Finlande] ; Petra Korpisalo [Finlande] ; Jarkko Soronen [Finlande] ; Seppo Kaijalainen [Finlande] ; Veli-Matti Lepp Nen [Finlande] ; Michael Jeltsch [Finlande] ; Seppo Yl Herttuala [Finlande] ; Kari Alitalo [Finlande] | Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle |
| 006547 |
A. Ghalamkarpour [Belgique] ; W. Holnthoner [Finlande] ; P. Saharinen [Finlande] ; L M Boon [Belgique] ; J B Mulliken [États-Unis] ; Kari Alitalo [Finlande] ; M. Vikkula [Belgique] | Recessive primary congenital lymphoedema caused by a VEGFR3 mutation |
| 006867 |
Terhi Karpanen ; Kari Alitalo [Finlande] | VEGF-D: a modifier of embryonic lymphangiogenesis |
| 006883 |
Marja Lohela ; Hanna Heloter ; Paula Haiko ; Daniel J. Dumont ; Kari Alitalo [Finlande] | Transgenic Induction of Vascular Endothelial Growth Factor-C Is Strongly Angiogenic in Mouse Embryos but Leads to Persistent Lymphatic Hyperplasia in Adult Tissues |
| 006A19 |
Terhi Karpanen [Finlande] ; Kari Alitalo [Finlande] | Molecular biology and pathology of lymphangiogenesis. |
| 006B60 |
Paula Haiko ; Taija Makinen ; Salla Keskitalo ; Jussi Taipale ; Marika J. Karkkainen ; Megan E. Baldwin ; Steven A. Stacker ; Marc G. Achen ; Kari Alitalo [Finlande] | Deletion of Vascular Endothelial Growth Factor C (VEGF-C) and VEGF-D Is Not Equivalent to VEGF Receptor 3 Deletion in Mouse Embryos▿ |
| 006C22 |
Hanna Sallinen [Finlande] ; Maarit Anttila [Finlande] ; Johanna Narvainen [Finlande] ; Jonna Koponen [Finlande] ; Kirsi Hamalainen [Finlande] ; Ivana Kholova [Finlande] ; Tommi Heikura [Finlande] ; Pyry Toivanen [Finlande] ; Veli-Matti Kosma [Finlande] ; Seppo Heinonen [Finlande] ; Kari Alitalo [Finlande] ; Seppo Yla-Herttuala [Finlande] | Antiangiogenic Gene Therapy With Soluble VEGFR-1, -2, and -3 Reduces the Growth of Solid Human Ovarian Carcinoma in Mice |
| 006C54 |
Andrew V. Benest [Royaume-Uni] ; Steven J. Harper [Royaume-Uni] ; Seppo Yla Herttuala [Finlande] ; Kari Alitalo [Finlande] ; David O. Bates [Royaume-Uni] | VEGF-C induced angiogenesis preferentially occurs at a distance from lymphangiogenesis |
| 007048 |
Satoshi Hirakawa [Japon] ; Lawrence F. Brown [États-Unis] ; Shohta Kodama [États-Unis] ; Karri Paavonen [Finlande] ; Kari Alitalo [Finlande] ; Michael Detmar [Suisse] | VEGF-C–induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites |
| 007071 |
Tuomas Tammela [Finlande] ; Anne Saaristo ; Tanja Holopainen ; Johannes Lyytikk ; Anna Kotronen ; Miia Pitkonen ; Usama Abo-Ramadan ; Seppo Yl Herttuala ; Tatiana V. Petrova ; Kari Alitalo [Finlande] | Therapeutic differentiation and maturation of lymphatic vessels after lymph node dissection and transplantation. |
| 007222 |
Taija M Kinen [Allemagne] ; Kari Alitalo [Finlande] | Lymphangiogenesis in development and disease. |
| 007297 |
Tuomas Tammela [Finlande] ; Yulong He ; Johannes Lyytikk ; Michael Jeltsch ; Johanna Markkanen ; Katri Pajusola ; Seppo Yl Herttuala ; Kari Alitalo [Finlande] | Distinct architecture of lymphatic vessels induced by chimeric vascular endothelial growth factor-C/vascular endothelial growth factor heparin-binding domain fusion proteins. |
| 007298 |
Lucie Kopfstein ; Tanja Veikkola ; Valentin G. Djonov ; Vanessa Baeriswyl ; Tibor Schomber ; Karin Strittmatter ; Steven A. Stacker ; Marc G. Achen ; Kari Alitalo [Finlande] ; Gerhard Christofori | Distinct Roles of Vascular Endothelial Growth Factor-D in Lymphangiogenesis and Metastasis |
| 007577 |
Kari Alitalo [Finlande] | Lymphangiogenesis in development and human disease |
| 007799 |
Anne Saaristo ; Tuomas Tammela ; Anniina F Rkkil ; Marika K Rkk Inen ; Erkki Suominen ; Seppo Yla-Herttuala ; Kari Alitalo [Finlande] | Vascular Endothelial Growth Factor-C Accelerates Diabetic Wound Healing |
| 007817 |
Tine V. Karlsen ; Marika J. Karkkainen ; Kari Alitalo [Finlande] ; Helge Wiig | Transcapillary fluid balance consequences of missing initial lymphatics studied in a mouse model of primary lymphoedema |
| 007849 |
Pia Lepp Nen [Finlande] ; Ivana Kholová [Finlande] ; Anssi J. M Hönen [Finlande] ; Kari Airenne [Finlande] ; Suvi Koota [Finlande] ; Hannu Mansukoski [Allemagne] ; Johanna N Rv Inen [Royaume-Uni] ; Maria Wirzenius [Finlande] ; Leena Alhonen [Finlande] ; Juhani J Nne [Finlande] ; Kari Alitalo [Finlande] ; Seppo Yl Herttuala [Finlande] | Short and Long-Term Effects of hVEGF-A165 in Cre-Activated Transgenic Mice |
| 007931 |
Terhi Karpanen ; Maria Wirzenius ; Taija M Kinen ; Tanja Veikkola ; Hidde J. Haisma ; Marc G. Achen ; Steven A. Stacker ; Bronislaw Pytowski ; Seppo Yl Herttuala ; Kari Alitalo [Finlande] | Lymphangiogenic Growth Factor Responsiveness Is Modulated by Postnatal Lymphatic Vessel Maturation |
| 007C40 |
Minoru Takemoto [Suède] ; Liqun He [Suède] ; Jenny Norlin [Suède] ; Jaakko Patrakka [Suède] ; Zhijie Xiao [Suède] ; Tatiana Petrova [Finlande] ; Cecilia Bondjers [Suède] ; Julia Asp [Suède] ; Elisabet Wallgard [Suède] ; Ying Sun [Suède] ; Tore Samuelsson [Suède] ; Petter Mostad [Suède] ; Samuel Lundin [Suède] ; Naoyuki Miura [Japon] ; Yoshikazu Sado [Japon] ; Kari Alitalo [Finlande] ; Susan E. Quaggin [Canada] ; Karl Tryggvason [Suède] ; Christer Betsholtz [Suède] | Large‐scale identification of genes implicated in kidney glomerulus development and function |
| 007E53 |
Guillermo Oliver [États-Unis] ; Kari Alitalo [Finlande] | The lymphatic vasculature: recent progress and paradigms. |
| 008030 |
Ugur Ozerdem ; Kari Alitalo [Finlande] ; Petri Salven ; Andrew Li | CONTRIBUTION OF BONE MARROW-DERIVED PERICYTE PRECURSOR CELLS TO CORNEAL VASCULOGENESIS |
| 008304 |
Kari Alitalo [Finlande] ; Tuomas Tammela [Finlande] ; Tatiana V. Petrova [Finlande] | Lymphangiogenesis in development and human disease |
| 008683 |
Anne Saaristo [Finlande] ; Tuomas Tammela ; Jari Timonen ; Seppo Yla-Herttuala ; Erkki Tukiainen ; Sirpa Asko-Seljavaara ; Kari Alitalo [Finlande] | Vascular endothelial growth factor-C gene therapy restores lymphatic flow across incision wounds. |
| 008769 |
Pipsa Saharinen [Finlande] ; Tuomas Tammela ; Marika J. Karkkainen ; Kari Alitalo [Finlande] | Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation. |
| 008829 |
Tatiana V. Petrova [Finlande] ; Terhi Karpanen ; Camilla Norrmén ; Russell Mellor ; Tomoki Tamakoshi ; David Finegold ; Robert Ferrell ; Dontscho Kerjaschki ; Peter Mortimer (dermatologue) [Royaume-Uni] ; Seppo Yl Herttuala ; Naoyuki Miura ; Kari Alitalo [Finlande] | Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis. |
| 008903 |
Elke A. Ober [États-Unis] ; Birgitta Olofsson [États-Unis] ; Taija M Kinen [Finlande] ; Suk-Won Jin [États-Unis] ; Wataru Shoji [Japon] ; Gou Young Koh [Corée du Sud] ; Kari Alitalo [Finlande] ; Didier Y R. Stainier [États-Unis] | Vegfc is required for vascular development and endoderm morphogenesis in zebrafish |
| 008904 |
Marika J. Karkkainen [Finlande] ; Paula Haiko [Finlande] ; Kirsi Sainio [Finlande] ; Juha Partanen [Finlande] ; Jussi Taipale [Finlande] ; Tatiana V. Petrova [Finlande] ; Michael Jeltsch [Finlande] ; David G. Jackson [Royaume-Uni] ; Marja Talikka [Finlande] ; Heikki Rauvala [Finlande] ; Christer Betsholtz [Suède] ; Kari Alitalo [Finlande] | Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins |
| 008E92 |
Michael Jeltsch [Finlande] ; Tuomas Tammela ; Kari Alitalo [Finlande] ; Jörg Wilting | Genesis and pathogenesis of lymphatic vessels. |
| 009259 |
Marja Lohela [Finlande] ; Anne Saaristo [Finlande] ; Tanja Veikkola [Finlande] ; Kari Alitalo [Finlande] | Lymphangiogenic growth factors, receptors and therapies |
| 009339 |
Lotta Jussila [Finlande] ; Kari Alitalo [Finlande] | Vascular growth factors and lymphangiogenesis. |
| 009340 |
Yan Zhou ; Michael Mcmaster ; Kirstin Woo ; Mary Janatpour ; Jean Perry ; Terhi Karpanen ; Kari Alitalo [Finlande] ; Caroline Damsky ; Susan J. Fisher | Vascular Endothelial Growth Factor Ligands and Receptors That
Regulate Human Cytotrophoblast Survival Are Dysregulated in Severe
Preeclampsia and Hemolysis, Elevated Liver Enzymes, and Low Platelets
Syndrome |
| 009351 |
Andrzej Szuba [États-Unis] ; Mihaela Skobe ; Marika J. Karkkainen ; William S. Shin ; David P. Beynet ; Ned B. Rockson ; Noma Dakhil ; Stan Spilman ; Michael L. Goris ; H William Strauss ; Thomas Quertermous ; Kari Alitalo [Finlande] ; Stanley G. Rockson | Therapeutic lymphangiogenesis with human recombinant VEGF-C. |
| 009353 |
Jörg Wilting [Allemagne] ; Maria Papoutsi ; Bodo Christ ; Kypros H. Nicolaides ; Constantin S. Von Kaisenberg ; Jörg Borges ; G Björn Stark ; Kari Alitalo [Finlande] ; Stanislav I. Tomarev ; Charlotte Niemeyer ; Jochen Rössler | The transcription factor Prox1 is a marker for lymphatic endothelial cells in normal and diseased human tissues. |
| 009409 |
T. M Kinen [Finlande] ; Kari Alitalo [Finlande] | Molecular mechanisms of lymphangiogenesis. |
| 009410 |
Kari Alitalo [Finlande] ; Peter Carmeliet | Molecular mechanisms of lymphangiogenesis in health and disease. |
| 009424 |
Marika J. Karkkainen [Finlande] ; Kari Alitalo [Finlande] | Lymphatic endothelial regulation, lymphoedema, and lymph node metastasis. |
| 009425 |
Anne Saaristo [Finlande] ; Tanja Veikkola [Finlande] ; Tuomas Tammela [Finlande] ; Berndt Enholm [Finlande] ; Marika J. Karkkainen [Finlande] ; Katri Pajusola [Suisse] ; Hansruedi Bueler [Suisse] ; Seppo Yl Herttuala [Finlande] ; Kari Alitalo [Finlande] | Lymphangiogenic Gene Therapy With Minimal Blood Vascular Side Effects |
| 009497 |
Anne Saaristo [Finlande] ; Tanja Veikkola ; Berndt Enholm ; Maija Hytönen ; Johanna Arola ; Katri Pajusola ; Païvi Turunen ; Michael Jeltsch ; Marika J. Karkkainen ; Dontscho Kerjaschki ; Hansruedi Bueler ; Seppo Yl Herttuala ; Kari Alitalo [Finlande] | Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes. |
| 009562 |
Yulong He [Finlande] ; Ken-Ichi Kozaki [Finlande] ; Terhi Karpanen [Finlande] ; Katsumi Koshikawa [Finlande] ; Seppo Yla-Herttuala [Finlande] ; Takashi Takahashi [Finlande] ; Kari Alitalo [Finlande] | Suppression of Tumor Lymphangiogenesis and Lymph Node Metastasis by Blocking Vascular Endothelial Growth Factor Receptor 3 Signaling |
| 009675 |
Tatiana V. Petrova [États-Unis] ; Taija M Kinen [États-Unis] ; Tomi P. M Kel [États-Unis] ; Janna Saarela [États-Unis] ; Ismo Virtanen [États-Unis] ; Robert E. Ferrell [États-Unis] ; David N. Finegold [États-Unis] ; Dontscho Kerjaschki [Autriche] ; Seppo Yl Erttuala [Finlande] ; Kari Alitalo [États-Unis, Finlande] | Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox‐1 homeobox transcription factor |
| 009692 |
Anne Saaristo [Finlande] ; Marika J. Karkkainen [Finlande] ; Kari Alitalo [Finlande] | Insights into the Molecular Pathogenesis and Targeted Treatment of Lymphedema |
| 009949 |
K. Iljin [Finlande] ; M J Karkkainen ; E C Lawrence ; M A Kimak ; M. Uutela ; J. Taipale ; K. Pajusola ; L. Alhonen ; M. Halmekytö ; D N Finegold ; R E Ferrell ; Kari Alitalo [Finlande] | VEGFR3 gene structure, regulatory region, and sequence polymorphisms. |
| 009A17 |
Terhi Karpanen [Finlande] ; Kari Alitalo [Finlande] | Lymphatic Vessels as Targets of Tumor Therapy? |
| 009A23 |
T. M Kinen [Finlande] ; L. Jussila ; T. Veikkola ; T. Karpanen ; M I Kettunen ; K J Pulkkanen ; R. Kauppinen ; D G Jackson ; H. Kubo ; S. Nishikawa ; S. Yl Herttuala ; Kari Alitalo [Finlande] | Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. |
| 009A76 |
Marika J. Karkkainen [Finlande] ; Anne Saaristo [Finlande] ; Lotta Jussila [Finlande] ; Kaisa A. Karila [Finlande] ; Elizabeth C. Lawrence [États-Unis] ; Katri Pajusola [Suisse] ; Hansruedi Bueler [Suisse] ; Anne Eichmann [France] ; Risto Kauppinen ; Mikko I. Kettunen ; Seppo Yl Herttuala [Finlande] ; David N. Finegold [États-Unis] ; Robert E. Ferrell [États-Unis] ; Kari Alitalo [Finlande] | A model for gene therapy of human hereditary lymphedema |
| 009E36 |
Marika J. Karkkainen [Finlande] ; Lotta Jussila [Finlande] ; Kari Alitalo [Finlande] ; Robert E. Ferrell ; David N. Finegold | Molecular regulation of lymphangiogenesis and targets for tissue oedema |
| 00A748 |
Alexandre Irrthum [Belgique] ; Marika J. Karkkainen ; Koen Devriendt ; Kari Alitalo [Finlande] ; Miikka Vikkula [Belgique] | Congenital Hereditary Lymphedema Caused by a Mutation That Inactivates VEGFR3 Tyrosine Kinase |
| 00A896 |
M. J. Karkkainen [Finlande] ; R. E. Ferrell [États-Unis] ; E. C. Lawrence [États-Unis] ; M. A. Kimak [États-Unis] ; K. L. Levinson [États-Unis] ; M. A. Mctigue [États-Unis] ; Kari Alitalo [Finlande] ; D. N. Finegold [États-Unis] | Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema |
| 00AC07 |
Silvana Breiteneder-Geleff ; Afschin Soleiman ; Heinrich Kowalski ; Reinhard Horvat ; Gabriele Amann ; Ernst Kriehuber ; Katja Diem ; Wolfgang Weninger ; Erwin Tschachler ; Kari Alitalo [Finlande] ; Dontscho Kerjaschki [Autriche] | Angiosarcomas Express Mixed Endothelial Phenotypes of Blood and Lymphatic Capillaries |
| 00AC81 |
Tatiana V. Petrova [Finlande] ; Taija Makinen [Finlande] ; Kari Alitalo [Finlande] | Signaling via Vascular Endothelial Growth Factor Receptors |
| 00AD97 |
Sabrina Mancardi [Italie] ; Giorgio Stanta [Italie] ; Nelson Dusetti [Italie] ; Marco Bestagno [Italie] ; Lotta Jussila [Finlande] ; Marina Zweyer [Italie] ; Giancarlo Lunazzi [Italie] ; Daniel Dumont [Canada] ; Kari Alitalo [Finlande] ; Oscar R. Burrone [Italie] | Lymphatic Endothelial Tumors Induced by Intraperitoneal Injection of Incomplete Freund's Adjuvant |
| 00B954 |
Su-Ja Oh [Allemagne] ; Markku M. Jeltsch [Finlande] ; Ralf Birkenh Ger [Allemagne] ; John E. G. Mccarthy [Allemagne] ; Herbert A. Weich [Allemagne] ; Bodo Christ [Allemagne] ; Kari Alitalo [Finlande] ; Jörg Wilting [Allemagne] | VEGF and VEGF-C: Specific Induction of Angiogenesis and Lymphangiogenesis in the Differentiated Avian Chorioallantoic Membrane |
| 012A43 |
Hung M. Bui ; David Enis [États-Unis] ; Marius R. Robciuc [Finlande] ; Harri J. Nurmi [Finlande] ; Jennifer Cohen ; Mei Chen ; Yiqing Yang ; Veerpal Dhillon ; Kathy Johnson [États-Unis] ; Hong Zhang [États-Unis] ; Robert Kirkpatrick [États-Unis] ; Elizabeth Traxler ; Andrey Anisimov [Finlande] ; Kari Alitalo [Finlande] ; Mark L. Kahn | Proteolytic activation defines distinct lymphangiogenic mechanisms for VEGFC and VEGFD |
| 012C15 |
Amanda W. Lund [États-Unis, Suisse] ; Marek Wagner [Norvège] ; Manuel Fankhauser [Suisse] ; Eli S. Steinskog [Norvège] ; Maria A. Broggi [Suisse] ; Stefani Spranger ; Thomas F. Gajewski [États-Unis] ; Kari Alitalo [Finlande] ; Hans P. Eikesdal [Norvège] ; Helge Wiig [Norvège] ; Melody A. Swartz [Suisse, États-Unis] | Lymphatic vessels regulate immune microenvironments in human and murine melanoma |
